Osteoporosis Medications and Your Oral Health

 
 

Understanding How Osteoporosis Medications Affect Oral Health

Certain medications prescribed to treat osteoporosis—such as bisphosphonates and denosumab—can impact the jawbone and oral tissues.
While these drugs are highly effective for preventing bone loss and fractures, they can occasionally lead to a rare but serious condition known as Medication-Related Osteonecrosis of the Jaw (MRONJ).

What Is MRONJ?

Medication-Related Osteonecrosis of the Jaw occurs when the jawbone fails to heal properly after dental surgery or trauma.
It can lead to:

  • Persistent jaw pain or swelling

  • Gum infection or exposed bone

  • Delayed healing after tooth extractions or implant placement

Although MRONJ is uncommon, the risk increases for patients receiving intravenous bisphosphonates or those undergoing dental procedures such as extractions, implants, or dentures while on therapy.

Bisphosphonates and Denosumab: What to Know

  • Bisphosphonates slow the natural bone resorption process to strengthen bones and reduce fracture risk.

  • Denosumab, a newer medication, works differently but has similar effects on bone turnover.

Both medications can reduce jawbone remodeling, making it harder for the mouth to heal after invasive dental procedures.
Denosumab has also been linked to a higher risk of gum infections or dental abscesses in some patients.

Protecting Your Dental Health During Osteoporosis Treatment

If you take medications for osteoporosis, it’s important to take preventive steps:

  • Maintain excellent oral hygiene and schedule regular dental checkups.

  • Inform your dentist about all medications and doses before any dental procedure.

  • Avoid unnecessary tooth extractions if possible.

  • Your physician and dentist may coordinate a temporary pause in therapy before surgical dental treatment to lower your MRONJ risk.

At CJ Henley, DMD, we work closely with your medical team to plan safe, evidence-based dental care for patients on bisphosphonates or denosumab.

The Bottom Line

Medications used to manage osteoporosis can affect oral health, particularly in relation to jawbone healing and gum health.