Fordyce Spots (Fordyce Granules)

Fordyce spots are the tiny yellow or white dots a lot of people notice one day on their lips or inside their cheeks, usually while looking closely in a mirror. They can look like goosebumps, grains of sand, or little pimples that never come to a head. They're one of the most common "is this normal?" questions we get, and the answer is almost always yes.

Short answer

Fordyce spots are tiny, painless, yellow-white bumps on the lips or inside the cheeks. They're normal oil glands that sit closer to the surface than usual, and most adults have some. They are not contagious, not an STI, and not cancer. They don't need treatment and usually stay for life. Leave them alone, and see a dentist if a spot grows, bleeds, hurts, or looks different from the rest.

Not sure this is what you have? Answer five quick questions in our mouth spot checker. It compares what you see with more than 40 common conditions and tells you how soon to have it looked at.

How commonMost adults have some
SizeAbout 1–3 mm each
Contagious?No
Usually noticedAround puberty or later
Medical nameEctopic sebaceous glands
Fordyce spots on the lips: many tiny, slightly raised, pale yellow-white dots scattered across the pink part of the lip
Fordyce spots on the lips. The dots are small, evenly sized, and pale yellow-white, and they sit just under the surface instead of on top of it. Photo: Superdisk, Wikimedia Commons, CC BY-SA 4.0

What are Fordyce spots?

Fordyce spots are small oil glands, the same kind of gland that keeps the skin on your face from drying out. Doctors call them ectopic sebaceous glands, which just means "oil glands in an unexpected place." On most of your skin, oil glands are attached to a hair. Fordyce spots aren't. They open straight onto the surface of the lip or the lining of the mouth, and because that lining is thin, you can see the yellowish oil through it.

You'll also hear them called Fordyce granules. Same thing. They're named after John Addison Fordyce, an American dermatologist who described them over a century ago.

The important part: they're normal anatomy. They aren't an infection, they aren't caused by poor hygiene, and they don't turn into anything else. Dentists see them on most adults during a routine dental exam, and we usually only mention them if you ask.

Why Fordyce spots show: an oil gland without a hair follicleTwo cross-sections side by side. On the left, ordinary facial skin, where the oil gland empties into a hair follicle below the surface. On the right, the lip or inner cheek, where an oil gland sits just under a thin lining with no hair, opens straight onto the surface, and makes a tiny yellow-white bump.Ordinary facial skinLip or inner cheek: a Fordyce spotHairSkin surfaceOil gland drainsinto the hair follicleHairfollicleThin, moist lining:the yellow shows throughOpens straightonto the surfaceOil gland,no hair follicleMost oil glands are tied to a hairEach spot is about 1–3 mm across
On most skin, oil glands empty into a hair follicle. A Fordyce spot is an oil gland with no hair attached, sitting just under the thin lining of the lip or cheek, so you see it as a tiny yellow-white bump. Illustration: CJ Henley, DMD.

What Fordyce spots look like

Once you know the pattern, Fordyce spots are easy to recognize. Look for:

  • Small, even dots, each about the size of a pinhead (1 to 3 mm). They tend to look alike instead of varying a lot in size.
  • Pale yellow, cream, or white color. On darker lips they can look almost skin-colored or faintly yellow.
  • Slightly raised or flat. Run your tongue over them and you may feel a faint, sandy texture, or nothing at all.
  • Clusters or scattered groups, sometimes a few, sometimes dozens. When they're packed tightly they can look like a pale, pebbly patch.
  • They stay put. They don't wipe off, don't crust, and don't come and go over a few days the way a sore does.

They're often easier to see when the lip is stretched, which is why people suddenly spot them while putting on lip balm or taking a close-up photo. Some people find they look more obvious at certain times, like after the lips get dry or chapped, but the spots themselves haven't changed.

If you've been searching for pictures of Fordyce spots and comparing them to your own mouth, the photo near the top of this page is a good typical example. What normal Fordyce spots don't look like: a single bump that's bigger than the rest, a sore, a blister with clear fluid, a crusted area, or a white patch with blurry edges. Those are worth having us look at.

Fordyce spots on lips and inside the cheeks

Fordyce spots on lips are what most people notice first, especially on the pink part (the vermilion) of the upper lip. Inside the mouth, the most common place is the inner cheek, often along the line where your back teeth meet and toward the back near the last molars. They can also show up on the inside of the lips.

They're unusual on the tongue, the gums, and the roof of the mouth. A spot in one of those places isn't automatically a problem, but it's a reason to have it checked so we're not assuming.

Where Fordyce spots usually show up on the lips and in the mouthDiagram of an open mouth with small yellow dots marking where Fordyce spots usually cluster: the pink part of the upper and lower lips, the inside of the lips, the inner cheeks along the bite line, and the area behind the last molars. The tongue, gums, and roof of the mouth are labeled as unusual places.Upper lip (pink part)the most common place people noticeTongue, gums, roofof the mouthunusual, have it checkedInner cheek, alongthe bite lineBehind the last molarsInside of the lipsLower lipInnercheekWhere Fordyce spots usually cluster
Fordyce spots favor the lips and the inner cheeks, especially toward the back. Spots on the tongue, gums, or roof of the mouth are uncommon and worth a look. Illustration: CJ Henley, DMD.

What causes Fordyce spots?

Nothing you did. Fordyce spots form during normal development, when some oil-gland tissue ends up in the lip and cheek lining instead of only in the skin. They're thought to be present from very early on, even in some newborns, but they're usually too small to notice in childhood.

Around puberty, hormones make oil glands everywhere on the body grow and get more active. That's when Fordyce spots typically become visible, and why so many people first notice them as teenagers or young adults. They often look a bit more prominent in adults than in kids.

What causes Fordyce spots on lips specifically? The same thing. The lips are a transition zone between skin and mouth lining, and the pink part is thin, so the glands show more easily there.

Things that don't cause them:

  • Sexual activity or an STI. Fordyce spots are not an infection of any kind.
  • Poor hygiene or diet.
  • Kissing, sharing drinks, or anything else you can catch from another person.

How common they are depends on who's counting and how closely they look. Studies range from a little over half of adults to more than 8 in 10. Either way, having them is the norm, not the exception.

Fordyce spots vs. look-alikes

A handful of other things can look like small white or yellow dots in the mouth. Here's how we tell them apart.

Could it be…What it usually looks likeHow it differs from Fordyce spots
Fordyce spotsMany tiny, even, pale yellow-white dots on the lips or inner cheeksPainless, don't wipe off, and stay the same for months or years
Oral thrushCreamy white patches on the tongue, cheeks, or palateThrush wipes off and leaves a red, sore spot underneath. It's a yeast infection and often burns.
Early cold sore blistersA small cluster of fluid-filled blisters on or at the edge of the lipCold sores tingle or burn first, then blister, break, and crust within days. Fordyce spots never crust and don't come and go.
MiliaFirm, pearly white bumps on the skin, often around the eyes or on the faceMilia are tiny trapped-keratin cysts on regular skin. They aren't usually on the pink of the lip or inside the mouth.
Oral papilloma (HPV)A single white or pink bump with a bumpy, cauliflower-like or finger-like surfaceA papilloma is usually one larger growth with a rough surface, not a spread of smooth pinpoint dots
LeukoplakiaA flat white patch that doesn't wipe off, often with blurry edgesLeukoplakia is a patch, not separate dots, and it needs an exam and sometimes a biopsy
Linea albaA thin white line along the inner cheek where the teeth meetLinea alba is a ridge from cheek rubbing or sucking. It's a line, not dots, though Fordyce spots can sit right next to it.

Two things point strongly toward Fordyce spots: they're symmetrical (often on both sides of the mouth or across the whole lip) and they've been there a long time without changing. A new single bump, a sore, or a patch is a different story. Our page on mucoceles covers the soft, clear bumps that pop up inside the lip after a bite, and our guide to oral fibromas covers firm, smooth lumps from cheek biting.

Symptoms: do Fordyce spots itch or hurt?

No. Fordyce spots on the lips and in the mouth have no symptoms. They don't itch, burn, sting, tingle, or bleed. Most people only know they're there because they saw them.

If a spot on your lip tingles or itches and then blisters, think cold sore. If the inside of your mouth burns and has white patches that rub off, think thrush. If a spot is sore, bleeding, or growing, it isn't behaving like a Fordyce spot, and we'd want to see it. The same goes for any patch or sore that hasn't healed in 2 weeks. Our page on the signs of oral cancer explains what to watch for, although most spots people worry about turn out to be harmless.

The one real "symptom" is how they make some people feel. If you're self-conscious about Fordyce spots on your lips, that's a legitimate concern, and there are cosmetic options covered below.

Do Fordyce spots go away?

Usually not. Fordyce spots are part of your normal anatomy, so they tend to stay for life. They may look more obvious in your teens and twenties and stay about the same after that. Some people feel they fade a little with age, and they can seem more or less visible depending on how dry or stretched your lips are.

If you had something removed and it came back, that's common too. Cosmetic treatments can reduce how they look, but the tissue that makes them is still there, and new spots can show up over time.

The good news is that "they won't go away" doesn't mean "they'll get worse." They don't spread like an infection and they don't turn into cancer.

What to do about Fordyce spots at home

Home care for Fordyce spots is mostly about not making things worse. There's nothing to cure.

  1. Check the pattern. Look in good light. Small, even, yellow-white dots on both sides of the lip or cheeks that don't hurt and have been there a while are classic Fordyce spots.
  2. Leave them alone. Don't squeeze, pick, scrub, or try to pop them. They aren't pimples. Squeezing can split the lip, cause bleeding, and leave a scar or an infected sore that's far more noticeable than the spots.
  3. Keep your lips moisturized. A plain lip balm helps with dryness and chapping, which can make the spots stand out more. Pick one with SPF if you're outside a lot. Jacksonville sun is hard on lips.
  4. Skip harsh home "removal" tricks. Toothpaste, lemon juice, apple cider vinegar, garlic, and essential oils don't remove Fordyce spots, and several of them can burn the thin skin of the lips.
  5. Take a photo. If you're unsure, a clear, close-up photo now gives you something to compare against in a few months. Fordyce spots won't change much. Something that does change deserves a visit.

Can you pop Fordyce spots?

  • Please don't. They aren't clogged pores. Squeezing may push out a little oily material, but the gland stays put and the spot comes back.
  • Squeezing can do real damage. Lip tissue is thin and bleeds easily. Picking can lead to infection, swelling, or a scar.
  • Don't take antibiotics or antifungals for them. There's no infection to treat.

Over-the-counter products and Fordyce spots

No drugstore product removes Fordyce spots. A few can help with comfort or appearance, and some are better avoided.

ProductWhat it doesThings to know
Plain lip balm or petroleum jellySoftens dry, chapped lips so the spots are less noticeableSafe for most people. Use a lip balm with SPF in the sun.
Tinted lip balm or lipstickCovers Fordyce spots on the lips for appearancePurely cosmetic. Matte, drying formulas can make texture more obvious.
Retinoid acne gels (adapalene)Treats acne on regular skinNot made for lips or the inside of the mouth and can irritate. There's no good evidence they remove Fordyce spots. Check with your doctor before using any retinoid if you're pregnant or trying to be.
Salicylic acid or benzoyl peroxideAcne treatments for skinNot for lips or mouth tissue. They can burn and peel without changing the spots.
Numbing gels (benzocaine)Temporary numbingNot needed, since Fordyce spots don't hurt. Never use benzocaine in children under 2.

How to get rid of Fordyce spots (removal options)

"How to get rid of Fordyce spots" is one of the most searched questions about them, so here's a straight answer. You don't need to remove them for your health. If they bother you cosmetically, removal is a dermatology question, and a dermatologist is the right person to talk to. The options that have been reported include:

  • Laser treatment. Carbon dioxide (CO2) laser and other lasers have been used to vaporize the spots on the lips. Reports are mostly small case series, but results have looked good cosmetically.
  • Micro-punch removal. A tiny round instrument removes individual spots under local anesthetic. It's more often used on genital skin than on lips.
  • Photodynamic therapy. A light-activated cream treatment that some dermatologists have tried.
  • Isotretinoin. A prescription acne pill that shrinks oil glands. A few people with acne have seen their Fordyce spots shrink while taking it, but in some cases the spots came back after stopping. It has serious side effects and absolutely can't be taken during pregnancy, so nobody prescribes it for Fordyce spots alone without a careful conversation.

A few things to know before you book anything. Most of the evidence comes from small numbers of patients. Any procedure on the lip can leave a scar or change in color, which may bother you more than the spots did. And Fordyce spots can come back after treatment, because the tissue that makes them is still there. For Fordyce spots on lips treatment, ask the dermatologist how many people they've treated, what the healing looks like, and what happens if the spots return.

What a dentist can do

For most people, the most useful thing we can do is tell you for sure what you're looking at.

  • Confirm what it is. In almost every case we can recognize Fordyce spots just by looking. No test, no biopsy, no prescription.
  • Look at everything else while we're there. We check the rest of your lips, cheeks, tongue, and throat during an exam, which is often what really puts people's minds at ease. If you want a focused look, ask about an oral cancer screening at your visit.
  • Sort out the look-alikes. Thrush, cold sores, papillomas, leukoplakia, and bite-related bumps each need different things, and some need treatment.
  • Biopsy or refer when something doesn't fit. A single larger bump, a spot that's growing, or one in an unusual place gets a closer look. When needed we can take a small biopsy or refer you, and that's the only way to know for certain what a spot is. Our oral medicine and diagnosis page explains how we work up mouth spots that don't have an obvious answer.
  • Point you to the right person for cosmetic removal. We don't remove Fordyce spots for cosmetic reasons. If you want them treated, we'll suggest you see a dermatologist.

Can you prevent Fordyce spots?

No, and you don't need to. They're a normal part of how lips and cheeks are built, so there's nothing to prevent. You can keep them from looking worse by not picking at them and keeping your lips from drying out. Regular checkups mean someone who knows what normal looks like in your mouth is keeping an eye on it.

Fordyce spots in babies, teens, pregnancy, and other areas of skin

Babies and young children

Fordyce spots have been reported in newborns, though they're much less common in young kids than in adults. In babies, small white or yellow spots are more often something else, like thrush, little cysts on the gums or palate that go away by themselves, or milk residue. Ask your pediatrician or dentist to take a look. Don't use benzocaine numbing products in children under 2.

Teens

This is when most people first notice Fordyce spots, right as hormones kick oil glands into gear. It's common to worry they're acne, a cold sore, or an STI. They're none of those. A quick check at a dental visit settles it.

Pregnancy

Fordyce spots don't need treatment during pregnancy. Skip retinoid products and don't start any cosmetic removal until after pregnancy and breastfeeding, unless your doctor says otherwise.

Fordyce spots on other skin

The same harmless oil glands can also appear on genital skin, where they're just as normal and not an STI. That's a question for your physician, dermatologist, or gynecologist, not your dentist, and it's worth having a doctor confirm it if you're unsure.

People with cancer treatment or a weak immune system

Fordyce spots behave the same way in everyone. But if you're going through chemotherapy or radiation, or your immune system is weakened, new white spots in the mouth are more likely to be thrush or another infection, so get them checked instead of assuming. Our head and neck cancer dental care page covers mouth care during treatment.

When to see a dentist about spots on your lips or cheeks

Make an appointment if:

  • You're not sure the spots are Fordyce spots and you'd like a professional opinion
  • One spot is bigger than the others, or a spot is growing or changing
  • The spots are on your tongue, gums, or the roof of your mouth
  • There's a white or red patch, not separate dots
  • White spots wipe off, burn, or leave a raw area
  • A spot appeared after an injury and isn't settling down after 2 weeks

Get care quickly if:

  • A spot or sore is bleeding, painful, or hasn't healed in 2 weeks
  • You have a lump in the mouth or neck, numbness, or trouble swallowing
  • You have blisters with fever, or you feel sick
  • Your immune system is weakened and new white spots have appeared

Fordyce spots FAQ

What are Fordyce spots?

Fordyce spots are tiny oil glands that show up as small yellow or white bumps on the lips or inside the cheeks. Unlike most oil glands, they aren't attached to a hair, so they open right at the surface where you can see them. They're a normal variation found in most adults, and they're harmless.

Are Fordyce spots contagious?

No. Fordyce spots aren't caused by a virus, bacteria, or fungus, so you can't catch them or spread them by kissing, oral sex, or sharing drinks. They aren't a sexually transmitted infection. They're part of your normal anatomy.

How do you get rid of Fordyce spots?

You don't have to, because they're harmless. If they bother you cosmetically, a dermatologist can discuss options such as laser treatment, micro-punch removal, or, in some acne patients, the prescription medicine isotretinoin. Evidence for these comes from small studies, and the spots can come back afterward. Home remedies and acne creams don't remove them.

How do I get rid of Fordyce spots on my lips?

Fordyce spots on the lips can be treated by a dermatologist, most often with a laser, but treatment is cosmetic and not medically needed. Lip treatments carry some risk of scarring or color change, and spots can return. In the meantime, a moisturizing lip balm or tinted lip product can make them less noticeable.

Do Fordyce spots go away?

Usually not. Fordyce spots are normal oil glands, so most people have them for life. They often become noticeable in the teens and twenties and then stay about the same. Some people find they look less obvious with age or when their lips are well moisturized.

What causes Fordyce spots?

Fordyce spots come from oil-gland tissue that forms in the lip and cheek lining during normal development. Hormones at puberty make oil glands bigger and more active, which is why the spots usually become visible in the teen years. They aren't caused by hygiene, diet, or sexual activity.

What causes Fordyce spots on the lips?

The same oil glands that cause Fordyce spots inside the cheeks also occur in the pink part of the lips. Lip skin is thin, so the pale yellow glands show through easily. They're especially common on the upper lip and tend to become more visible after puberty.

Do Fordyce spots itch?

No. Fordyce spots on the lips and in the mouth don't itch, hurt, or burn. If a spot on your lip itches or tingles and then blisters, it's more likely an early cold sore. Any spot that hurts, bleeds, or changes should be looked at by a dentist or doctor.

Can you pop Fordyce spots?

You shouldn't. Fordyce spots aren't pimples or clogged pores, and squeezing won't make them go away. Picking at the thin lip skin can cause bleeding, infection, and scarring that look worse than the spots ever did.

Are Fordyce spots an STD?

No. Fordyce spots are not a sexually transmitted disease and aren't caused by any infection. They're normal oil glands that most adults have. Because they can also appear on genital skin, people sometimes worry they're an STI, so if you're unsure about spots in that area, see your physician to confirm.

Are Fordyce spots cancer?

No. Fordyce spots are normal tissue and don't turn into cancer. Signs that something else may be going on include a single spot that grows, a sore that doesn't heal in 2 weeks, a red or white patch, bleeding, or a lump. Those should be examined, and a biopsy is the only way to know for sure what a spot is.

What's the difference between Fordyce spots and oral thrush?

Fordyce spots are tiny, even, yellow-white dots that don't wipe off and don't hurt. Oral thrush is a yeast infection that forms creamy white patches, and those patches wipe off to leave a red, sore area underneath. Thrush often burns and usually needs antifungal medicine, while Fordyce spots need no treatment.

Can kids get Fordyce spots?

Yes, but they're much more common in teens and adults. They've been seen in newborns, though in babies small white spots are more often thrush or harmless cysts on the gums or palate. They typically become noticeable around puberty, when oil glands grow. A pediatrician or dentist can confirm what you're seeing.

Not sure if those spots are Fordyce spots?

If you're in the Jacksonville area and want a second set of eyes on spots on your lips or inside your cheeks, we're glad to take a look. Most of the time it's a quick, reassuring answer. When something doesn't fit the pattern, we'll tell you what we think it is and what should happen next.

Related conditions

Sources

  1. Akintoye SO, Mupparapu M. Clinical evaluation and anatomic variation of the oral cavity. Dermatol Clin. 2020;38(4):399–411.
  2. Primary Care Dermatology Society. Fordyce spots (syn. Fordyce's granules). Clinical guidance; updated 2021.
  3. Olivier JH. Fordyce granules on the prolabial and oral mucous membranes of a selected population. SADJ. 2006;61(2):72–74.
  4. Pietkiewicz P, et al. Differentiating Fordyce spots from their common simulators using ultraviolet-induced fluorescence dermatoscopy: retrospective study. Diagnostics (Basel). 2023;13(5):985.
  5. Ocampo-Candiani J, et al. Treatment of Fordyce spots with CO2 laser. Dermatol Surg. 2003;29(8):869–871.
  6. Mutizwa MM, Berk DR. Dichotomous long-term response to isotretinoin in two patients with Fordyce spots. Pediatr Dermatol. 2014;31(1):73–75.

This page is for general education and isn't a diagnosis. Every mouth is different. If you have a sore you're worried about, see your dentist or physician. Photos marked Wikimedia Commons are used under their listed licenses and may have been cropped or resized.